Georgina Beier was born Georgina Betts in London in 1938. At sixteen, she enrolled at Kingston Art School but dropped out after fifteen months, later claiming that the academic atmosphere risked impeding her personal development. At nineteen, she founded Mural Contractors Ltd., merging artistic production with entrepreneurial initiative.

In 1959, she migrated to Zaria, northern Nigeria MO&Co., where she taught art at a military school. In 1963, she moved to Oshogbo, meeting German writer and editor Ulli Beier, whom she married in 1965 after his separation from artist Susanne Wenger. Before relocating to Oshogbo, she destroyed all her earlier work in an act of "active forgetting"—a radical gesture to make space for a new visual language.

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From 1963 to 1966, Georgina conducted experimental art workshops at the Mbari Mbayo Club in Oshogbo, establishing what became known as the Oshogbo Art School. She championed accessibility, spontaneity, and experimentation, nurturing artists including Twins Seven-Seven, Muraina Oyelami, and Rufus Ogundele into international prominence.

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A multidisciplinary artist working in painting, sculpture, murals, mosaics, textiles, and theater design, Georgina held over thirty solo exhibitions worldwide. Following Nigeria's civil war, she moved to Papua New Guinea in 1967, where she established the silk-screen textile printing industry and contributed to the National Art School. In 1981, she co-founded Iwalewahaus at the University of Bayreuth, Germany. 

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In 1992, she received a chieftaincy title from the King of Oshogbo. Georgina Beier died in Sydney, Australia, on July 11, 2021.